You, like a small percentage of the population, maybe inquisitive about why it's so crucial to protect personnel, products, and the ecosystem against hazardous waste and contamination during normal activities. Because of the vital importance of lab research, the equipment you can choose must be designed and developed to address the different needs of your workplace, as well as operate within a performance envelope that ensures the greatest level of protection and notable security under requesting laboratory conditions.
It's critical to understand everything you can about the abilities, restrictions, and proper usage of certain biosafety cabinets, and the suitability of every confinement cabinet for your protection must be certified by an occupational hygienist or certified safety officer.
What is a biological safety cabinet, also identified as a biosafety cabinet or BSC? A biosafety cabinet, also widely recognized as a biosafety cabinet or BSC, is a ventilated workstation where research and processes can be carried out. Protecting scientists in the lab is a primary priority in almost all BSCs. Some BSCs also act as sample guardians.
However, to choose the finest Biological safety cabinet for a laboratory, a researcher must narrow down his options and understand how it can be used, as well as the biological agents that may be managed. Biosafety in Microbiological and Biomedical Laboratories (BMBL) 6th Edition specifies the required biosafety level for various agents.
- ●Biosafety Level 1 (BSL-1) is required while operating with identified and characterized strains of live biological agents which are not expected to induce disease in immunocompromised human adults
- ●Biosafety Level 2 (BSL-2) is are necessaryfor moderate-risk chemicals that induce human disease of variable severity via ingesting, percutaneous, or mucosal exposure”
- ●Biosafety Level 3 (BSL-3) is essential for agents having a recognized tendency for aerosol transmission, for pathogens that may induce significant and dangerous lethal illnesses, and for agents which are native or foreign in origin.
- ●Biosafety Level 4 (BSL-4) is used when researchers operate with foreign pathogens that represent a significant risk exposure of life-threatening disease through contagious aerosols and where no treatment is available.
Types of Biological safety cabinets
Biocompare's page on Class I, II, and III Biosafety Cabinets provide a good summary of BSCs. Here's how the BSC categories compare:
- ●Class I: These BSCs are ductless or ducted, and they safeguard the operator as well as the laboratory surroundings but just not the specimen. In BSL 1, 2, and 3 operations, a Class I BSC can be employed for containment. They ensures the safety of personnel and the environment when dealing with chemicals and powders. Air enters the cabinets into the front aperture and passes via a built-in air vent, HEPA and/or Carbon filter, protecting both the user and the surroundings. At the back of the worktop, air escapes the cabinet. The inward circulation through the front opening, as well as ventilation of the exhausted air, are used to regulate the departure of any airborne particles collected within the cabinets.
- ●Class II: These BSCs fulfill all of the functions of a Class I BSC and additionally provide specimen safety. Type A1, Type A2, Type B1, and Type B2 are some of the subclasses. “Lowest possible input speeds and exhaust systems” are the distinctive characteristics of these varieties, according to the Biocompare page. The people, ecological, and product protection standards for the Class 2 Biological Safety cabinet must be met.
- ●Class III: These BSCs, generally termed gloveboxes, are entirely contained and can be utilized in operations with a BSL of 1–4. The cabinet is intended for use in Biosafety Level 4 labs containing elevated bioweapons, where utmost confinement and security are essential. Ebola, the Lassa virus, or any other harmful or transmissible virus are instances.
Now that you know how much BSL is required for a certain process and which sort of BSC to choose, Let's move on to another topic in this article: where to buy pointers.
How to work with biological cabinets?
- Wash hands before and after working with the cabinets
- Protective clothing must be worn while using the hood. Long clothing, gloves and a robe.
- Smooth airflow must be maintained in the laboratory
- The vapors must be cleaned regularly
A Biological safety cabinet purchases advantages from the study as well as technical assistance in all situations. According to NSF/ANSI 49 – 2019, "before purchasing a biosafety cabinet (BSC), a biosafety expert must be informed." Many factors need to be considered when selecting a BSC. Some organizations have BSC sales authorized by a biosafety specialist after an appointment with the customer, engineer, and technician.” For one reason, the BSC must be open enough just to allow the access required for a given application while also keeping lab staff secure, but examine that information carefully.
A BSC must make the most of the fuel generated to do the activity at hand. It is ineffective if a BSC enhances energy economy at the cost of functionality, such as by requiring a longer reach into the working area, a thinner air barrier, or restricted thrust to drive through a saturated HEPA filter over time.
MRC- Laboratory Equipment provides a wide range of Biological safety cabinets that include Class 1,2,3. Contact us for more details and product customization